Which T-score results indicate a 10-year probability of major osteoporotic fracture of 20% or greater?

A T-score of -2.0 indicates that the bone density is significantly lower than the average for a healthy young adult population, which is typically used as the baseline for these measurements. This score suggests that the individual is in the osteoporotic range according to the World Health Organization's classification of bone mineral density.

In this context, a T-score of -2.0 correlates strongly with a higher risk of fractures. Studies have shown that individuals with a T-score of -2.5 or lower face a greater than 20% probability of experiencing a major osteoporotic fracture over the next 10 years. While a less negative T-score (like -1.0 or -1.5) may indicate lower levels of risk, they do not reach the threshold needed for a minimum 20% risk of major osteoporotic fractures.

Thus, a T-score of -2.0 aligns with the increased fracture risk that defines significant osteoporotic conditions. This is why a T-score of -2.0 is the appropriate answer for indicating a 10-year probability of major osteoporotic fractures of 20% or greater.