Which lipoprotein is known for carrying cholesterol that can deposit into peripheral vascular disease?

The lipoprotein that is primarily associated with carrying cholesterol that can deposit into peripheral vascular disease is Low-Density Lipoprotein, commonly referred to as LDL. LDL particles transport cholesterol from the liver to peripheral tissues, including blood vessels. When there is an excess of LDL in the bloodstream, it can lead to the accumulation of cholesterol in the walls of arteries, contributing to atherosclerosis, which is a major factor in the development of peripheral vascular disease.

In contrast, High-Density Lipoprotein (HDL) is often characterized as "good" cholesterol because it helps transport cholesterol away from the arteries back to the liver for excretion or reuse, thereby reducing the risk of cardiovascular diseases. Very Low-Density Lipoprotein (VLDL) primarily carries triglycerides but can also contribute to the formation of LDL. Chylomicrons are involved in transporting dietary lipids from the intestines to other locations in the body and do not have the same role in the development of atherosclerosis as LDL.

Therefore, LDL is distinctly known for its role in depositing cholesterol in peripheral tissues, making it the correct choice in this context.