Which condition is related to an increase in glomerular filtration rate (GFR) during pregnancy?

During pregnancy, the body undergoes significant physiological changes, including adaptations in renal function. One of the notable changes is an increase in glomerular filtration rate (GFR). This increase is primarily due to hormonal changes, such as elevated hCG and increased levels of progesterone, which lead to vasodilation and increased blood flow to the kidneys.

In this context, the increase in GFR during pregnancy is directly related to enhanced drug elimination. As the GFR rises, the kidneys become more efficient at filtering blood, which in turn increases the clearance of drugs and metabolites from the body. This is particularly important for the management of medications during pregnancy, as it impacts dosages and the timing of drug administration, ensuring that therapeutic levels are maintained while minimizing potential harm to the developing fetus.

The other conditions listed—dehydration, organ failure, and cervical dilation—do not directly correlate with the physiological increase in GFR experienced during pregnancy. Dehydration typically leads to decreased GFR, organ failure adversely affects renal function, and cervical dilation is related to labor and delivery processes but not to GFR changes in the context of pregnancy.