Which condition is characterized by inflammation of the bone and joint?

The condition characterized by inflammation of the bone and joint is osteoarthritis. This degenerative joint disease typically results from the wear and tear of cartilage that cushions the ends of bones in the joints, leading to pain, stiffness, and swelling. While osteoarthritis is primarily known for its effects on cartilage, it also involves some degree of inflammatory response as the underlying structures of the joint, including the bones and synovial membranes, may become involved.

In comparing this to the other conditions listed, rheumatoid arthritis is an autoimmune disorder that causes significant inflammation but has a distinct mechanism involving systemic processes. Gout is characterized by the deposition of urate crystals in the joints, leading to acute inflammatory episodes, while psoriatic arthritis, associated with psoriasis, also has inflammatory components but its pathophysiology is different from that of osteoarthritis. Each of these conditions involves inflammation, but osteoarthritis stands out due to its chronic nature and association with joint degeneration.