What symptom is typically present with acute CMV infection in adults?

In adults, acute cytomegalovirus (CMV) infection can present with a variety of nonspecific symptoms, and chills are commonly reported during the acute phase of infection. This is part of the body's immune response to the viral presence and can indicate systemic involvement. CMV may also cause mild flu-like symptoms, and chills often accompany fevers and malaise that are typical in viral infections.

While other symptoms such as jaundice, chronic cough, and severe headache can occur in various conditions, they are not typical or specific indicators of acute CMV infection in adults. For instance, jaundice is more commonly associated with liver-related diseases or infections such as hepatitis, rather than a straightforward viral illness like CMV. Chronic cough is also indicative of respiratory conditions rather than a viral infection primarily affecting other systems. Severe headache may occur in some cases but is not as universally recognized as part of the symptomatology of acute CMV infection. Hence, chills are a more characteristic symptom of this condition in adults.