What is the usual administration route for Misoprostol during the third stage of labor?

The usual administration route for Misoprostol during the third stage of labor is rectally. This method is preferred due to its effectiveness and fast absorption rate when compared to other routes. Administering Misoprostol rectally allows for rapid access to systemic circulation, which is crucial in managing the third stage of labor, especially for preventing postpartum hemorrhage.

While oral administration can be effective in other contexts, it may have a delayed onset of action, which is not suitable for emergency situations typically encountered in the third stage of labor. Subcutaneous routes are generally more common for other medications but are not the standard for Misoprostol in this specific context. Intradermal administration is not a recommended route for this medication, as it does not facilitate the desired rapid systemic effect. Thus, rectal administration stands out as the most effective and reliable option during the third stage of labor.