What is Ospemifene classified as?

Ospemifene is classified as a selective estrogen receptor modulator (SERM). This classification means that it functions by selectively binding to estrogen receptors in various tissues in the body. Unlike traditional estrogens, which have a uniform effect on all estrogen receptors, SERMs can act as estrogen agonists in some tissues while functioning as antagonists in others. This selective action can provide therapeutic benefits, particularly in addressing vaginal atrophy and dyspareunia resulting from menopause, without some of the risks associated with traditional hormone replacement therapies.

In contrast to natural estrogens, which directly replace estrogen in the body, or hormone replacement therapy that typically involves administering estrogens, Ospemifene's unique mechanism of action is that it is designed to mimic the beneficial effects of estrogen specifically in the vaginal and urinary tissues. It does not belong to the category of anti-inflammatory drugs, which generally target inflammation rather than estrogen receptor pathways. Ospemifene's classification as a SERM emphasizes its specific role in managing menopausal symptoms while potentially minimizing side effects linked to estrogen therapy.