What does the quad screen test assess in maternal blood?

The quad screen test assesses specific markers in maternal blood, including maternal serum alpha-fetoprotein (AFP), human chorionic gonadotropin (hCG), estriol, and inhibin A. By measuring these four substances, the test helps evaluate the risk of certain genetic abnormalities in the fetus, such as Down syndrome and neural tube defects.

This comprehensive approach to screening allows healthcare providers to gain important insights into fetal health and development. It is particularly useful during the second trimester of pregnancy when the likelihood of detecting potential issues is higher. The quad screen test does not address the presence of uterine fibroids, nor does it evaluate maternal blood type or Rh factor, which are distinct assessments used for different purposes in prenatal care.

The inclusion of both alpha-fetoprotein and other markers aligns with the test’s objective of providing a broader risk assessment for genetic conditions rather than focusing solely on a single aspect.